Scholarship: Fully funded
Degree: Ph.D. or M.D/Ph.D
Subjects: biomedical
Nationality: International Students
Location: USA
Closing Date: open until filled
Start date: immediately
Scholarship Description:
UT Southwestern, one of the premier academic medical centers in the U.S., integrates pioneering biomedical research with exceptional clinical care and education. The faculty of more than 2,700 is responsible for groundbreaking medical advances and is committed to translating science-driven research quickly to new clinical treatments. The institution’s faculty includes many distinguished members, including 6 who have been awarded Nobel Prizes, 23 members of the National Academy of Sciences, 17 members of the National Academy of Medicine and 13 investigators of the Howard Hughes Medical Institute.
Our lab’s research focuses on uncovering the fundamental molecular mechanisms by which inflammation is initiated, propagated and terminated when no longer needed (see examples of our recent work: Nature. 2018 Aug;560(7717):198-203; Cell. 2016 Feb 25;164(5):896-910; Nat Commun. 2017 Apr 11;8:15004; Cell. 2016 Jul 14;166(2):288-298; Nat Immunol. 2017 Jul 19;18(8):861-869; Trends in Immunology. 2019 Dec;40(12):1120-1133).
By utilizing a combination of biochemical, genetic, molecular, immunological, live-imaging and histological tools as well as single-cell “omics” approaches, we aim to decipher the multifaceted roles of mitochondria in innate immune regulation. Currently, we focus on understanding how mitochondria sense the loss of cellular homeostasis, and transmit stress signals to the rest of the cell (e.g. cytoplasm, ER and nucleus) to ultimately induce immune activation. Additionally, we are also interested in understanding how common disease risk factors (e.g. aging and dietary obesity) affect mitochondrial signaling, thereby permitting the onset of chronic inflammation that accelerates disease progression.
Eligibility Criteria:
We are looking to recruit talented postdoctoral fellows with research experience in immunology, cell biology, biochemistry and/or cancer biology. Potential candidates should have a Ph.D. or M.D/Ph.D degree in a related biomedical field. Women and underrepresented minorities in academia are strongly encouraged to apply.
Application Procedure:
If interested, please send CV and three reference letters to [email protected]
